Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.57 |
| ▸ | STS | P08842 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | MGLL | Q99685 | 2/20 | 0.47 |
| ▸ | ESRRA | P11474 | 8/20 | 0.47 |
| ▸ | RXRA | P19793 | 2/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70460 | 0.87 | NOTUM (0.58) | NOTUMSTSCA5AESRRARXRA | |
| SCHEMBL28033861 | 0.85 | NOTUM (0.57) | NOTUMSTSESRRARXRAGRIN1 | |
| SCHEMBL30398809 | 0.81 | CA1 (0.59) | NOTUMCA5AESRRANPC1RAB9A | |
| SCHEMBL19691104 | 0.81 | ESRRA (0.63) | NOTUMFAAHMGLLESRRAPARP1 | |
| SCHEMBL30398916 | 0.75 | ESRRA (0.46) | NOTUMCA5AFAAHMGLLESRRA | |
| SCHEMBL30399748 | 0.73 | NOTUM (0.43) | NOTUMCA5AESRRANPC1RAB9A | |
| SCHEMBL15964868 | 0.73 | CA5A (0.65) | CA5ASMN1; SMN2 | |
| SCHEMBL30808842 | 0.73 | MAOA (0.51) | NOTUMCA5AESRRA | |
| SCHEMBL30398926 | 0.73 | ESRRA (0.56) | NOTUMESRRA | |
| SCHEMBL13728028 | 0.73 | ESRRA (0.59) | NOTUMESRRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283920-B | 2, 4-disubstituted pyridine compound and application thereof | 贵州医科大学 | 2024-04-16 | — | — | CN | claimed |
| CN-116283920-A | 2, 4-disubstituted pyridine compound and application thereof | 贵州医科大学 | 2023-06-23 | — | — | CN | claimed |
| CN-116283920-B | 2, 4-disubstituted pyridine compound and application thereof | 贵州医科大学 | 2024-04-16 | — | — | CN | disclosed |
| CN-116283920-A | 2, 4-disubstituted pyridine compound and application thereof | 贵州医科大学 | 2023-06-23 | — | — | CN | disclosed |