Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14775168 | 1.00 | MEN1 (0.37) | MEN1KMT2AALDH1A1SIRT6TDP1 | |
| SCHEMBL27778060 | 0.83 | SIRT6 (0.38) | MEN1KMT2AALDH1A1SIRT6TDP1 | |
| SCHEMBL31278788 | 0.82 | SMN1; SMN2 (0.40) | MEN1KMT2AALDH1A1GRM5SMN1; SMN2 | |
| SCHEMBL30937725 | 0.82 | ALDH1A1 (0.38) | MEN1KMT2AALDH1A1SIRT6TDP1 | |
| SCHEMBL21823124 | 0.82 | SMN1; SMN2 (0.40) | MEN1KMT2AALDH1A1GRM5SMN1; SMN2 | |
| SCHEMBL25396719 | 0.81 | SIRT6 (0.41) | MEN1KMT2AALDH1A1SIRT6TDP1 | |
| SCHEMBL29535934 | 0.81 | MEN1 (0.46) | MEN1KMT2AALDH1A1SIRT6TDP1 | |
| SCHEMBL1615193 | 0.81 | MEN1 (0.46) | MEN1KMT2AALDH1A1SIRT6TDP1 | |
| SCHEMBL24097752 | 0.80 | PLAU (0.42) | MEN1KMT2AALDH1A1TDP1GRM5 | |
| SCHEMBL29829126 | 0.79 | SIRT6 (0.48) | MEN1KMT2ASIRT6GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025128777-A1 | INDAZOLE DERIVATIVES USEFUL AS INHIBITORS OF NOD-LIKE RECEPTOR PROTEIN 3 | MERCK SHARP & DOHME LLC (US) | 2025-06-19 | — | — | WO | disclosed |
| CN-109789146-B | Chemokine receptor modulators and uses thereof | 拉普特医疗公司 | 2023-04-18 | — | — | CN | disclosed |