Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3032157 | 0.93 | HTT (0.35) | HTT | |
| SCHEMBL3032623 | 0.91 | HTT (0.33) | HTT | |
| SCHEMBL3026323 | 0.89 | RECQL (0.36) | — | |
| SCHEMBL3038062 | 0.89 | RAB9A (0.34) | — | |
| SCHEMBL3037429 | 0.83 | HTT (0.39) | HTT | |
| SCHEMBL3036403 | 0.82 | RECQL (0.38) | — | |
| SCHEMBL3035865 | 0.80 | HTT (0.43) | HTT | |
| SCHEMBL978451 | 0.80 | NPC1 (0.38) | HTT | |
| SCHEMBL3034059 | 0.79 | RECQL (0.40) | HTT | |
| SCHEMBL3037028 | 0.79 | POLB (0.37) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013092942-A1 | USE OF AMINOBENZAMIDE DERIVATIVES FOR CONTROLLING ANIMAL PARASITES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-06-27 | — | — | WO | disclosed |
| US-8236828-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2012-08-07 | — | — | US | disclosed |
| EP-2212304-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-21 | — | — | EP | disclosed |
| US-20100216850-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-08-26 | — | — | US | disclosed |
| EP-2212304-A1 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2010-08-04 | — | — | EP | disclosed |
| US-20100048652-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-02-25 | — | — | US | disclosed |
| WO-2009049844-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-04-23 | — | — | WO | disclosed |
| EP-2046765-A1 | INSECTICIDAL COMPOUNDS | Syngeta Participations AG (CH) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008012027-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2008-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216850-A1 | INSECTICIDAL COMPOUNDS | CHRM1, ACHE, CHRM2 | HTT 1178/4885 |
| US-20100048652-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, CHRM2 | HTT 2065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.