Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 13/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 10/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CD74 | P04233 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 3/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.36 |
| ▸ | TEK | Q02763 | 2/20 | 0.35 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20416663 | 1.00 | ADORA2A (0.51) | ADORA2AADORA2BADORA1GPR55MEN1 | |
| SCHEMBL20401454 | 0.90 | GPR55 (0.53) | ADORA2AADORA2BADORA1GPR55MEN1 | |
| SCHEMBL30401467 | 0.90 | GPR55 (0.53) | ADORA2AADORA2BADORA1GPR55MEN1 | |
| SCHEMBL20436386 | 0.90 | ADORA2A (0.55) | ADORA2AADORA2BADORA1GPR55MEN1 | |
| SCHEMBL20442127 | 0.87 | TEK (0.47) | ADORA2AADORA2BADORA1CD74MIF | |
| SCHEMBL20417191 | 0.86 | ADORA2A (0.46) | ADORA2AADORA2BADORA1MEN1KMT2A | |
| SCHEMBL30401143 | 0.86 | ADORA2A (0.46) | ADORA2AADORA2BADORA1KDRTEK | |
| SCHEMBL30401930 | 0.86 | ADORA2A (0.46) | ADORA2AADORA2BADORA1GPR55CD74 | |
| SCHEMBL20401210 | 0.86 | ADORA2A (0.46) | ADORA2AADORA2BADORA1GPR55CD74 | |
| SCHEMBL20401029 | 0.86 | ADORA2A (0.46) | ADORA2AADORA2BADORA1KDRTEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116768859-A | Azolopyrimidines for the treatment of cancer related disorders | 艾库斯生物科学有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-110214012-B | Azolopyrimidines for the treatment of cancer related disorders | 艾库斯生物科学有限公司 | 2023-05-09 | — | — | CN | disclosed |