Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | TEK | Q02763 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20401454 | 1.00 | GPR55 (0.53) | GPR55MEN1KMT2AKDRTEK | |
| SCHEMBL20416663 | 0.90 | ADORA2A (0.51) | GPR55MEN1KMT2AKDRTEK | |
| SCHEMBL30401205 | 0.90 | ADORA2A (0.51) | GPR55MEN1KMT2AKDRTEK | |
| SCHEMBL20436391 | 0.90 | GPR55 (0.51) | GPR55MEN1KMT2AKDRTEK | |
| SCHEMBL20401259 | 0.88 | ADORA2A (0.43) | GPR55KDRTEKADORA2AADORA2B | |
| SCHEMBL20442127 | 0.88 | TEK (0.47) | KDRTEKADORA2AADORA2BADORA1 | |
| SCHEMBL20417191 | 0.87 | ADORA2A (0.46) | MEN1KMT2AKDRADORA2AADORA2B | |
| SCHEMBL20400379 | 0.87 | GPR55 (0.43) | GPR55ADORA2AADORA2BADORA1KCNH2 | |
| SCHEMBL30401166 | 0.87 | GPR55 (0.43) | GPR55ADORA2AADORA2BADORA1KCNH2 | |
| SCHEMBL30401930 | 0.87 | ADORA2A (0.46) | GPR55KDRTEKADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116768859-A | Azolopyrimidines for the treatment of cancer related disorders | 艾库斯生物科学有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-110214012-B | Azolopyrimidines for the treatment of cancer related disorders | 艾库斯生物科学有限公司 | 2023-05-09 | — | — | CN | disclosed |