SCHEMBL30401351

SCHEMBL30401351

COc1ccc(Cl)cc1S(=O)(=O)Nc1cncc(C(N)=O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALPL P05186 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30781409 1.00 ALPL (1.00) ALPL
SCHEMBL15211830 1.00 ALPL (1.00) ALPL
SCHEMBL15211836 0.90 ALPL (1.00) ALPL
SCHEMBL15212066 0.88 ALPL (1.00) ALPL
SCHEMBL15211893 0.88 ALPL (0.81) ALPL
SCHEMBL15212019 0.87 ALPL (1.00) ALPL
SCHEMBL15212064 0.87 ALPL (1.00) ALPL
SCHEMBL15211983 0.86 ALPL (1.00) ALPL
SCHEMBL16376113 0.86 ALPL (0.76) ALPL
SCHEMBL15212157 0.85 ALPL (1.00) ALPL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230149374-A1 METHODS AND COMPOSITIONS FOR TREATING ATHEROSCLEROSIS Sanford Burnham Prebys Medical Discovery Institute 2023-05-18 US claimed
WO-2026102093-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF TAU-RELATED DISORDERS VOYAGER THERAPEUTICS, INC. (US) 2026-05-15 WO disclosed
EP-4705488-A1 AAV CAPSID VARIANTS AND USES THEREOF Voyager Therapeutics, Inc. (US) 2026-03-11 EP disclosed
WO-2025235734-A2 AAV CAPSID VARIANTS AND USES THEREOF VOYAGER THERAPEUTICS, INC. (US) 2025-11-13 WO disclosed
EP-4565597-A2 COMPOSITIONS AND METHODS FOR CROSSING THE BLOOD BRAIN BARRIER Voyager Therapeutics, Inc. (US) 2025-06-11 EP disclosed
WO-2025100970-A1 TNAP INHIBITORY COMPOUND AND USE THEREOF 주식회사 레드엔비아 2025-05-15 WO disclosed
WO-2024229425-A1 AAV CAPSID VARIANTS AND USES THEREOF VOYAGER THERAPEUTICS, INC. (US) 2024-11-07 WO disclosed
WO-2024030976-A2 COMPOSITIONS AND METHODS FOR CROSSING THE BLOOD BRAIN BARRIER VOYAGER THERAPEUTICS, INC. (US) 2024-02-08 WO disclosed
WO-2023169327-A1 CRYSTAL FORM OF PYRIDAZINE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF 贝达药业股份有限公司 2023-09-14 WO disclosed
US-20230149374-A1 METHODS AND COMPOSITIONS FOR TREATING ATHEROSCLEROSIS Sanford Burnham Prebys Medical Discovery Institute 2023-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230149374-A1 METHODS AND COMPOSITIONS FOR TREATING ATHEROSCLEROSIS TNNI3, TNNT2, ACP3 ALPL 14/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.