Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | KIF5B | P33176 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25374364 | 1.00 | EGFR (0.41) | EGFRLMNAMAPTMEN1KMT2A | |
| SCHEMBL25375186 | 0.89 | HTT (0.39) | EGFRLMNAMAPTMEN1KMT2A | |
| SCHEMBL30402693 | 0.88 | TNF (0.43) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL25374957 | 0.88 | TNF (0.43) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL25376211 | 0.86 | LMNA (0.40) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL30402650 | 0.86 | LMNA (0.40) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL25373487 | 0.85 | ALDH3A1 (0.47) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL25373687 | 0.85 | MAPT (0.40) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL25376024 | 0.84 | PDGFRB (0.39) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL25373684 | 0.84 | LRRK2 (0.44) | LMNAMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096718-A | Aryl amide compound, pharmaceutical composition containing same, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-05-09 | — | — | CN | disclosed |