Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.64 |
| ▸ | LMNA | P02545 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.64 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.64 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.64 |
| ▸ | FBP1 | P09467 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | UBE2N | P61088 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | ABL2 | P42684 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3064358 | 0.94 | MAPT (0.66) | MAPTLMNASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL6802414 | 0.94 | MAPT (0.72) | MAPTLMNASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL3064354 | 0.94 | MAPT (0.66) | MAPTLMNASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL6802411 | 0.94 | MAPT (0.72) | MAPTLMNASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL18331459 | 0.89 | MAPT (0.54) | MAPTLMNASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL10975057 | 0.89 | SMN1; SMN2 (0.63) | MAPTLMNASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL10975054 | 0.89 | SMN1; SMN2 (0.63) | MAPTLMNASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL9513655 | 0.89 | ALDH1A1 (0.54) | MAPTLMNASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL9513661 | 0.89 | ALDH1A1 (0.54) | MAPTLMNASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL29198777 | 0.87 | LMNA (0.52) | MAPTLMNASMN1; SMN2ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4392402-A1 | SYNTHESIS ROUTES TO ACCESS MDMA PRODRUGS BY USING CONTROLLED AND NON-CONTROLLED INTERMEDIATES | Mind Medicine, Inc. (US) | 2024-07-03 | — | — | EP | disclosed |
| WO-2023028022-A1 | SYNTHESIS ROUTES TO ACCESS MDMA PRODRUGS BY USING CONTROLLED AND NON-CONTROLLED INTERMEDIATES | Mind Medicine, Inc. (US) | 2023-03-02 | — | — | WO | disclosed |