Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25169268 | 1.00 | GPR35 (0.31) | GPR35 | |
| SCHEMBL25172583 | 0.78 | PDPK1 (0.36) | — | |
| SCHEMBL25168095 | 0.78 | — | — | |
| SCHEMBL25167692 | 0.76 | GPR35 (0.31) | GPR35 | |
| SCHEMBL30433615 | 0.76 | GPR35 (0.31) | GPR35 | |
| SCHEMBL25467561 | 0.74 | PDE4B (0.32) | — | |
| SCHEMBL4166956 | 0.68 | KDM4E (0.38) | GPR35 | |
| SCHEMBL22866890 | 0.67 | HPGD (0.37) | GPR35 | |
| SCHEMBL31373103 | 0.67 | PDPK1 (0.36) | GPR35 | |
| SCHEMBL31337031 | 0.63 | MAPK1 (0.33) | GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4426702-A1 | CONDENSED-PYRAZINE AMINE DERIVATIVES FOR TREATING SCA3 | Skyhawk Therapeutics, Inc. (US) | 2024-09-11 | — | — | EP | disclosed |
| EP-4426704-A1 | CONDENSED PYRIDAZINE AMINE DERIVATIVES TREATING SCA3 | Skyhawk Therapeutics, Inc. (US) | 2024-09-11 | — | — | EP | disclosed |
| WO-2023081857-A1 | CONDENSED PYRIDAZINE AMINE DERIVATIVES TREATING SCA3 | SKYHAWK THERAPEUTICS, INC. (US) | 2023-05-11 | — | — | WO | disclosed |
| WO-2023081858-A1 | CONDENSED-PYRAZINE AMINE DERIVATIVES FOR TREATING SCA3 | SKYHAWK THERAPEUTICS, INC. (US) | 2023-05-11 | — | — | WO | disclosed |