Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056100 | 0.87 | NPSR1 (0.49) | MEN1KMT2AHTTPOLBALDH1A1 | |
| SCHEMBL14596143 | 0.76 | KMT2A (0.35) | MEN1KMT2AHTTPOLBALDH1A1 | |
| SCHEMBL28629085 | 0.76 | NPSR1 (0.40) | MEN1KMT2AHTTPOLBALDH1A1 | |
| SCHEMBL9057389 | 0.75 | HPGD (0.43) | MEN1KMT2AHTTPOLBNPSR1 | |
| SCHEMBL471978 | 0.74 | NPSR1 (0.49) | MEN1KMT2AHTTPOLBALDH1A1 | |
| SCHEMBL14020795 | 0.74 | NPSR1 (0.52) | MEN1KMT2AHTTPOLBALDH1A1 | |
| SCHEMBL10431511 | 0.73 | NPSR1 (0.49) | MEN1KMT2AHTTPOLBALDH1A1 | |
| SCHEMBL3790918 | 0.71 | DPP4 (0.52) | KMT2ATAAR1DPP4MYC | |
| SCHEMBL2552588 | 0.70 | NPSR1 (0.44) | MEN1KMT2AHTTPOLBALDH1A1 | |
| SCHEMBL31212640 | 0.70 | NPSR1 (0.44) | MEN1KMT2AHTTPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113416149-B | Biaryl axial chiral compound synthesized by nitrogen heterocyclic carbene catalysis and preparation method thereof | 贵州大学 | 2023-04-18 | — | — | CN | disclosed |