Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30401760 | 0.87 | MEN1 (0.41) | NPSR1KMT2AMEN1POLBHTT | |
| SCHEMBL28629085 | 0.87 | NPSR1 (0.40) | NPSR1KMT2AMEN1POLBHTT | |
| SCHEMBL9057389 | 0.86 | HPGD (0.43) | NPSR1KMT2AMEN1POLBHTT | |
| SCHEMBL471978 | 0.85 | NPSR1 (0.49) | NPSR1KMT2AMEN1POLBHTT | |
| SCHEMBL14020795 | 0.85 | NPSR1 (0.52) | NPSR1KMT2AMEN1POLBHTT | |
| SCHEMBL10431511 | 0.84 | NPSR1 (0.49) | NPSR1KMT2AMEN1POLBHTT | |
| SCHEMBL31212640 | 0.81 | NPSR1 (0.44) | NPSR1KMT2AMEN1POLBHTT | |
| SCHEMBL2552588 | 0.81 | NPSR1 (0.44) | NPSR1KMT2AMEN1POLBHTT | |
| SCHEMBL28811105 | 0.81 | NPSR1 (0.46) | NPSR1KMT2AMEN1POLBHTT | |
| SCHEMBL25797515 | 0.78 | POLB (0.50) | NPSR1KMT2AMEN1POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511558-B1 | Process for the resolution of racemates and associates of diastereoisomers | HOFFMANN LA ROCHE (CH) | 1996-10-23 | — | — | EP | claimed |
| JP-5148278-A | — | — | None | — | — | JP | disclosed |
| US-5334766-A | Process for the resolution of racemic diphosphine oxides | HOFFMANN-LA ROCHE INC. (US) | 1994-08-02 | — | — | US | disclosed |
| JP-H05148278-A | RESOLUTION OF RACEMIC BODY | F HOFFMANN LA ROCHE AG | 1993-06-15 | — | — | JP | disclosed |