Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 9/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.35 |
| ▸ | TEK | Q02763 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20417073 | 1.00 | KLKB1 (0.39) | KLKB1ADORA2BCYP19A1HDAC2HDAC8 | |
| SCHEMBL20436696 | 0.91 | KLKB1 (0.41) | KLKB1ADORA2BCYP19A1HDAC2HDAC8 | |
| SCHEMBL30402093 | 0.89 | ADORA2A (0.47) | ADORA2BADORA2AADORA1 | |
| SCHEMBL20401424 | 0.89 | ADORA2A (0.47) | ADORA2BADORA2AADORA1 | |
| SCHEMBL30401891 | 0.89 | ADORA2A (0.47) | ADORA2BADORA2AADORA1 | |
| SCHEMBL30401846 | 0.89 | ADORA2A (0.47) | ADORA2BADORA2AADORA1 | |
| SCHEMBL20416705 | 0.89 | ADORA2A (0.47) | ADORA2BADORA2AADORA1 | |
| SCHEMBL20401434 | 0.89 | ADORA2A (0.47) | ADORA2BADORA2AADORA1 | |
| SCHEMBL30401212 | 0.86 | CYP19A1 (0.41) | KLKB1ADORA2BCYP19A1HDAC2HDAC8 | |
| SCHEMBL20416734 | 0.86 | CYP19A1 (0.41) | KLKB1ADORA2BCYP19A1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116768859-A | Azolopyrimidines for the treatment of cancer related disorders | 艾库斯生物科学有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-110214012-B | Azolopyrimidines for the treatment of cancer related disorders | 艾库斯生物科学有限公司 | 2023-05-09 | — | — | CN | disclosed |