SCHEMBL20417073

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30401933	1.00	KLKB1 (0.39)	KLKB1ADORA2BCYP19A1HDAC2HDAC8
	SCHEMBL20436696	0.91	KLKB1 (0.41)	KLKB1ADORA2BCYP19A1HDAC2HDAC8
	SCHEMBL30402093	0.89	ADORA2A (0.47)	ADORA2BADORA2AADORA1
	SCHEMBL20401424	0.89	ADORA2A (0.47)	ADORA2BADORA2AADORA1
	SCHEMBL30401891	0.89	ADORA2A (0.47)	ADORA2BADORA2AADORA1
	SCHEMBL30401846	0.89	ADORA2A (0.47)	ADORA2BADORA2AADORA1
	SCHEMBL20416705	0.89	ADORA2A (0.47)	ADORA2BADORA2AADORA1
	SCHEMBL20401434	0.89	ADORA2A (0.47)	ADORA2BADORA2AADORA1
	SCHEMBL30401212	0.86	CYP19A1 (0.41)	KLKB1ADORA2BCYP19A1HDAC2HDAC8
	SCHEMBL20416734	0.86	CYP19A1 (0.41)	KLKB1ADORA2BCYP19A1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.