Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 4/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 5/20 | 0.34 |
| ▸ | CSF1R | P07333 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 6/20 | 0.33 |
| ▸ | HTR2C | P28335 | 6/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | STK3 | Q13188 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22124485 | 0.93 | PTK6 (0.37) | PTK6LCKEGFRCSF1RCCR2 | |
| SCHEMBL22124563 | 0.92 | PTK6 (0.36) | PTK6 | |
| SCHEMBL22123725 | 0.89 | PTK6 (0.47) | PTK6LCK | |
| SCHEMBL30171867 | 0.89 | PTK6 (0.47) | PTK6LCK | |
| SCHEMBL25176442 | 0.88 | PTK6 (0.40) | PTK6LCKEGFR | |
| Iodide SCHEMBL28982230 | 0.88 | PTK6 (0.39) | PTK6LCKEGFR | |
| SCHEMBL24112330 | 0.86 | PTK6 (0.39) | PTK6LCKEGFR | |
| SCHEMBL28982185 | 0.86 | PTK6 (0.39) | PTK6LCKEGFR | |
| SCHEMBL30171986 | 0.85 | PTK6 (0.51) | PTK6LCK | |
| SCHEMBL24112346 | 0.84 | PTK6 (0.39) | PTK6LCKEGFRSTK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898630-B1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2023-05-10 | — | — | EP | claimed |