Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4A3 | P38919 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 3/20 | 0.43 |
| ▸ | TDO2 | P48775 | 3/20 | 0.43 |
| ▸ | RHEB | Q15382 | 6/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30396135 | 0.83 | NOTUM (0.43) | KDM4EMEN1KMT2AKDRFBP1 | |
| SCHEMBL3959096 | 0.82 | EIF4A3 (0.53) | EIF4A3IDO1TDO2RHEBGRIN1 | |
| SCHEMBL30310764 | 0.82 | EIF4A3 (0.53) | EIF4A3IDO1TDO2RHEBGRIN1 | |
| SCHEMBL22394891 | 0.80 | IDO1 (0.65) | EIF4A3IDO1TDO2RHEBGRIN1 | |
| SCHEMBL24020852 | 0.74 | IDO1 (0.58) | EIF4A3IDO1TDO2RHEBGRIN1 | |
| SCHEMBL30817219 | 0.74 | IDO1 (0.58) | EIF4A3IDO1TDO2RHEBGRIN1 | |
| SCHEMBL30396556 | 0.73 | RHEB (0.55) | EIF4A3IDO1TDO2RHEBGRIN1 | |
| SCHEMBL1145047 | 0.72 | HRH4 (0.60) | EIF4A3DAOHPGDKDM4EMEN1 | |
| SCHEMBL28463825 | 0.72 | FBP1 (0.63) | EIF4A3KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL24189623 | 0.71 | EIF4A3 (0.68) | EIF4A3IDO1TDO2RHEBGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096714-A | Antiviral compounds for the treatment of coronavirus, picornavirus and norovirus infections | 安力高医药股份有限公司 | 2023-05-09 | — | — | CN | disclosed |