Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 3/20 | 0.35 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | ITGAL | P20701 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CRHBP | P24387 | 2/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.32 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30403900 | 0.89 | MAP3K14 (0.35) | MAP3K14ITGB2ICAM1ITGALAPP | |
| SCHEMBL30403810 | 0.81 | MAP3K14 (0.41) | MAP3K14ITGB2ICAM1ITGALSMN1; SMN2 | |
| SCHEMBL30403909 | 0.77 | ITGB2 (0.40) | MAP3K14ITGB2ICAM1ITGALSMN1; SMN2 | |
| SCHEMBL17729338 | 0.72 | BACE1 (0.36) | MAP3K14ITGB2ICAM1ITGALAPP | |
| SCHEMBL1350187 | 0.71 | AKR1B1 (0.35) | MAP3K14APPBACE1MAPTLMNA | |
| SCHEMBL30403463 | 0.69 | ITGB2 (0.43) | MAP3K14ITGB2ICAM1ITGALSMN1; SMN2 | |
| SCHEMBL30402655 | 0.69 | MAP3K14 (0.40) | MAP3K14ITGB2ICAM1ITGALSMN1; SMN2 | |
| SCHEMBL30403679 | 0.66 | MAP3K14 (0.37) | MAP3K14ITGB2ICAM1ITGALALDH1A1 | |
| SCHEMBL13725421 | 0.62 | ITGB2 (0.43) | MAP3K14ITGB2ICAM1ITGALMAPT | |
| SCHEMBL16661511 | 0.61 | ITGB2 (0.37) | MAP3K14ITGB2ICAM1ITGALMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11634395-B2 | Sulfonamide compound or salt thereof | Taiho Pharmaceutial Co., Ltd. (JP) | 2023-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11634395-B2 | Sulfonamide compound or salt thereof | RNASEH1, SNRPA1, RRM2 | MAP3K14 3138/4885ITGB2 4839/4885ICAM1 4875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.