Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 4/20 | 0.37 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.34 |
| ▸ | ITGAL | P20701 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | CRHBP | P24387 | 2/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | RARA | P10276 | 1/20 | 0.30 |
| ▸ | RARB | P10826 | 1/20 | 0.30 |
| ▸ | RARG | P13631 | 1/20 | 0.30 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30403463 | 0.87 | ITGB2 (0.43) | MAP3K14ITGB2ICAM1ITGALLMNA | |
| SCHEMBL30403909 | 0.81 | ITGB2 (0.40) | MAP3K14ITGB2ICAM1ITGALLMNA | |
| SCHEMBL7031384 | 0.77 | ITGB2 (0.40) | MAP3K14ITGB2ICAM1ITGALLMNA | |
| SCHEMBL29295492 | 0.72 | MAP3K14 (0.44) | MAP3K14HTTGAAALDH1A1RARA | |
| SCHEMBL23362642 | 0.71 | MAP3K14 (0.43) | MAP3K14LMNASMN1; SMN2HTTGAA | |
| SCHEMBL20554069 | 0.71 | MAP3K14 (0.43) | MAP3K14 | |
| SCHEMBL24162776 | 0.71 | ITGB2 (0.44) | MAP3K14ITGB2ICAM1ITGALLMNA | |
| SCHEMBL11444836 | 0.69 | MAP3K14 (0.41) | MAP3K14LMNASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL2632863 | 0.68 | ITGB2 (0.46) | MAP3K14ITGB2ICAM1ITGALLMNA | |
| SCHEMBL19852058 | 0.68 | AKR1B1 (0.37) | ITGB2ICAM1ITGALAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11634395-B2 | Sulfonamide compound or salt thereof | Taiho Pharmaceutial Co., Ltd. (JP) | 2023-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11634395-B2 | Sulfonamide compound or salt thereof | RNASEH1, SNRPA1, RRM2 | MAP3K14 3138/4885ITGB2 4839/4885ICAM1 4875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.