Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | NOS3 | P29474 | 3/20 | 0.48 |
| ▸ | NOS1 | P29475 | 3/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 6/20 | 0.46 |
| ▸ | DRD2 | P14416 | 5/20 | 0.46 |
| ▸ | DRD5 | P21918 | 5/20 | 0.46 |
| ▸ | DRD3 | P35462 | 5/20 | 0.46 |
| ▸ | DRD4 | P21917 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24110550 | 1.00 | HSD17B10 (0.50) | HSD17B10KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL24109783 | 0.92 | KDM4E (0.60) | HSD17B10KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL10815104 | 0.85 | KMT2A (0.57) | HSD17B10KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL25818515 | 0.82 | ALDH1A1 (0.54) | HSD17B10KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL12061308 | 0.81 | HRH3 (0.62) | HSD17B10ALDH1A1HDAC1HDAC6HRH3 | |
| SCHEMBL2675622 | 0.81 | NOS3 (0.53) | HSD17B10KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL24110325 | 0.79 | HDAC1 (0.52) | HSD17B10HDAC1HDAC6HRH3DRD1 | |
| SCHEMBL19871391 | 0.78 | HSD17B10 (0.47) | HSD17B10HDAC1HDAC6HRH3DRD1 | |
| SCHEMBL1450332 | 0.77 | ALDH1A1 (0.82) | KDM4EALDH1A1LMNAMAPTPTK2B | |
| SCHEMBL10816704 | 0.77 | HSD17B10 (0.51) | HSD17B10HDAC1HDAC6HRH3DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4165049-A1 | ISOTRYPTAMINE PSYCHOPLASTOGENS AND USES THEREOF | Delix Therapeutics, Inc. (US) | 2023-04-19 | — | — | EP | disclosed |