Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK2 | Q9HBH9 | 5/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | HTR2B | P41595 | 3/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | PRNP | P04156 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24110362 | 1.00 | MKNK2 (0.36) | MKNK2HTR2AHTR2CHTR2BPRMT5 | |
| SCHEMBL25299990 | 1.00 | MKNK2 (0.36) | MKNK2HTR2AHTR2CHTR2BPRMT5 | |
| SCHEMBL18926936 | 0.84 | MKNK2 (0.39) | MKNK2HTR2AHTR2CHTR2BPRMT5 | |
| SCHEMBL25301570 | 0.82 | HTR2C (0.52) | HTR2AHTR2CHTR2BCYP1A2 | |
| SCHEMBL24110230 | 0.82 | HTR2C (0.52) | HTR2AHTR2CHTR2BCYP1A2 | |
| SCHEMBL30404228 | 0.82 | HTR2C (0.52) | HTR2AHTR2CHTR2BCYP1A2 | |
| SCHEMBL25818036 | 0.78 | HTR2A (0.38) | HTR2AHTR2CHTR2BCYP1A2 | |
| SCHEMBL25818021 | 0.78 | MTNR1A (0.47) | HTR2AHTR2CHTR2BCYP2D6CYP1A2 | |
| SCHEMBL5068124 | 0.76 | MKNK2 (0.42) | MKNK2HTR2AHTR2CHTR2BPRMT5 | |
| SCHEMBL24110604 | 0.76 | HTR2C (0.47) | MKNK2HTR2AHTR2CEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4165049-A1 | ISOTRYPTAMINE PSYCHOPLASTOGENS AND USES THEREOF | Delix Therapeutics, Inc. (US) | 2023-04-19 | — | — | EP | disclosed |