Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PRCP | P42785 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 3/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1951212 | 0.90 | PPM1B (0.37) | PRCPHCAR2 | |
| SCHEMBL27550910 | 0.84 | MAPT (0.42) | ALDH1A1HPGD | |
| SCHEMBL7189528 | 0.84 | MAPT (0.42) | ALDH1A1HPGD | |
| SCHEMBL1417951 | 0.84 | MAPT (0.42) | ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL4283062 | 0.83 | MAPT (0.44) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2920606 | 0.83 | MAPT (0.44) | ALDH1A1 | |
| Acetic Acid SCHEMBL6729875 | 0.80 | MAPT (0.43) | ALDH1A1LMNA | |
| SCHEMBL11881200 | 0.80 | NAAA (0.50) | ALDH1A1TSHRNAAAHCAR2LMNA | |
| SCHEMBL1387029 | 0.79 | — | — | |
| SCHEMBL2638667 | 0.79 | PRCP (0.51) | ALDH1A1ATMPRCPHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4168002-A1 | METHODS FOR DELAYING, PREVENTING, AND TREATING ACQUIRED RESISTANCE TO RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2023-04-26 | — | — | EP | disclosed |