Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.61 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 7/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | GPR142 | Q7Z601 | 2/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14188300 | 0.76 | CDC7 (1.00) | CDC7GRM5GSK3BKDM5BROCK2 | |
| SCHEMBL5000027 | 0.73 | CDC7 (0.83) | CDC7GRM5GSK3BKDM5BROCK2 | |
| SCHEMBL17398392 | 0.71 | KDM4E (0.39) | — | |
| SCHEMBL30403363 | 0.70 | GRM5 (0.46) | CDC7GRM5GSK3BCYP1A2AR | |
| SCHEMBL30405199 | 0.70 | CDC7 (0.46) | CDC7GRM5GSK3BARPIK3CA | |
| SCHEMBL2927871 | 0.69 | — | — | |
| SCHEMBL3549357 | 0.69 | KMT2A (0.33) | ROCK2 | |
| SCHEMBL30403338 | 0.68 | GRM5 (0.44) | CDC7GRM5CYP1A2ARPIK3CA | |
| Trifluoroacetic Acid SCHEMBL4714169 | 0.67 | CDC7 (0.78) | CDC7GRM5GSK3B | |
| SCHEMBL18802950 | 0.67 | GRM5 (0.40) | GRM5AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116171280-A | Casein kinase 1 delta modulators | 詹森药业有限公司 | 2023-05-26 | — | — | CN | disclosed |