Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 2/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 9/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GALR2 | O43603 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 3/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.38 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | IDE | P14735 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30405336 | 0.93 | PDGFRB (0.41) | PDGFRBOPRD1OPRK1PDGFRAHTT | |
| SCHEMBL30406372 | 0.87 | KIT (0.49) | MTNR1BPDGFRBPDGFRAAKT1 | |
| SCHEMBL25229793 | 0.84 | AKT1 (0.42) | MTNR1BPDGFRBHTTAKT1HPGD | |
| SCHEMBL30406045 | 0.82 | MAPK7 (0.44) | MTNR1BENPP2ATXN2MAPK7 | |
| SCHEMBL19032194 | 0.81 | KIT (0.44) | MTNR1BPDGFRBPDGFRAAKT1 | |
| SCHEMBL30405237 | 0.81 | KIT (0.44) | AKT1 | |
| SCHEMBL25280892 | 0.81 | KIT (0.44) | AKT1 | |
| SCHEMBL30405888 | 0.81 | PDGFRB (0.41) | MTNR1BPDGFRBOPRD1OPRK1PDGFRA | |
| SCHEMBL30405875 | 0.80 | PDGFRB (0.39) | MTNR1BPDGFRBOPRD1OPRK1PDGFRA | |
| SCHEMBL25281209 | 0.80 | MEN1 (0.44) | MTNR1BAKT1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4444300-A2 | INHIBITORS OF MENIN-MLL INTERACTION | Bala Therapeutics, Inc. (US) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023107696-A2 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |