Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK7 | Q13164 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 11/20 | 0.42 |
| ▸ | ATXN2 | Q99700 | 11/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25232266 | 0.86 | MAPK7 (0.47) | MAPK7EPHX2MTNR1BKIT | |
| SCHEMBL30405747 | 0.86 | HTT (0.48) | MTNR1BENPP2ATXN2KIT | |
| SCHEMBL30405719 | 0.86 | MAPK7 (0.47) | MAPK7EPHX2MTNR1BKIT | |
| SCHEMBL25423050 | 0.85 | MAPK7 (0.48) | MAPK7EPHX2MTNR1BENPP2ATXN2 | |
| SCHEMBL30405798 | 0.82 | OPRD1 (0.43) | MTNR1BENPP2ATXN2 | |
| SCHEMBL30405783 | 0.82 | MTNR1B (0.42) | MAPK7MTNR1BENPP2ATXN2 | |
| SCHEMBL30405888 | 0.82 | PDGFRB (0.41) | MTNR1BENPP2ATXN2 | |
| SCHEMBL30405875 | 0.81 | PDGFRB (0.39) | MTNR1BENPP2ATXN2 | |
| SCHEMBL30405814 | 0.81 | HTT (0.38) | MTNR1BENPP2ATXN2 | |
| SCHEMBL30406292 | 0.80 | OPRD1 (0.37) | ENPP2ATXN2HRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4444300-A2 | INHIBITORS OF MENIN-MLL INTERACTION | Bala Therapeutics, Inc. (US) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023107696-A2 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |