Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 12/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GALR2 | O43603 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | IDE | P14735 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30405783 | 0.93 | MTNR1B (0.42) | PDGFRBOPRD1OPRK1PDGFRAKDM4E | |
| SCHEMBL31501691 | 0.87 | KIT (0.49) | PDGFRBPDGFRAAKT1 | |
| SCHEMBL25274939 | 0.84 | AKT1 (0.42) | PDGFRBSMYD3AKT1MEN1KMT2A | |
| SCHEMBL30406086 | 0.81 | KIT (0.44) | MEN1 | |
| SCHEMBL30406372 | 0.80 | KIT (0.49) | PDGFRBPDGFRAAKT1 | |
| SCHEMBL25274694 | 0.77 | CYP2D6 (0.41) | HTTSMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL30406292 | 0.77 | OPRD1 (0.37) | OPRD1OPRK1KDM4ELMNAMAPT | |
| SCHEMBL30406045 | 0.77 | MAPK7 (0.44) | MAPK7 | |
| SCHEMBL25229793 | 0.77 | AKT1 (0.42) | PDGFRBHTTHPGDAKT1MEN1 | |
| SCHEMBL30405843 | 0.76 | OPRD1 (0.36) | OPRD1OPRK1LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4444300-A2 | INHIBITORS OF MENIN-MLL INTERACTION | Bala Therapeutics, Inc. (US) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023107696-A2 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |