Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 6/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | CLK3 | P49761 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.37 |
| ▸ | CAMKK2 | Q96RR4 | 4/20 | 0.35 |
| ▸ | CAMKK1 | Q8N5S9 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 3/20 | 0.35 |
| ▸ | TDO2 | P48775 | 3/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | SGK1 | O00141 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | SGK3 | Q96BR1 | 1/20 | 0.34 |
| ▸ | SGK2 | Q9HBY8 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25519884 | 1.00 | DYRK1A (0.38) | DYRK1ACLK2CLK3PIM1PIM3 | |
| SCHEMBL30407715 | 0.89 | DYRK1A (0.50) | DYRK1ACLK2CLK3DYRK1BCAMKK2 | |
| SCHEMBL25519828 | 0.89 | DYRK1A (0.50) | DYRK1ACLK2CLK3DYRK1BCAMKK2 | |
| SCHEMBL25519953 | 0.84 | TDO2 (0.51) | DYRK1ACLK2CLK3CAMKK2CAMKK1 | |
| SCHEMBL26175933 | 0.83 | DYRK1B (0.38) | DYRK1APIM1PIM3PIM2DYRK1B | |
| SCHEMBL30346921 | 0.82 | ACP1 (0.41) | DYRK1ACLK2CLK3CAMKK2BRD4 | |
| SCHEMBL25518054 | 0.82 | ACP1 (0.41) | DYRK1ACLK2CLK3CAMKK2BRD4 | |
| SCHEMBL25157721 | 0.81 | TDO2 (0.45) | DYRK1ACLK2CLK3DYRK1BTDO2 | |
| SCHEMBL30406687 | 0.81 | TDO2 (0.45) | DYRK1ACLK2CLK3DYRK1BTDO2 | |
| SCHEMBL30406815 | 0.81 | CAMKK2 (0.39) | DYRK1ACLK2CLK3PIM1PIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167133-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF | VICKERS VENTURE FUND VI PTE. LTD. (SG) | 2023-06-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167133-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF | DYRK1A, DYRK1B, DYRK2 | DYRK1A 1/4885CLK2 466/4885CLK3 1147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.