Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1586237 | 0.86 | GPR119 (0.50) | GPR119HPGDRECQLEPHX1 | |
| SCHEMBL9348417 | 0.85 | USP30 (0.53) | GPR119HPGD | |
| SCHEMBL3578707 | 0.85 | GPR119 (0.46) | GPR119HPGDRECQLEPHX1 | |
| SCHEMBL3578711 | 0.85 | GPR119 (0.46) | GPR119HPGDRECQLEPHX1 | |
| SCHEMBL3578710 | 0.85 | GPR119 (0.46) | GPR119HPGDRECQLEPHX1 | |
| SCHEMBL13537033 | 0.81 | NR1H2 (0.45) | GPR119HPGDALDH1A1RECQLEPHX1 | |
| SCHEMBL8661760 | 0.81 | GPR119 (0.64) | GPR119HPGDRECQLEPHX1 | |
| SCHEMBL20744928 | 0.79 | DPP7 (0.35) | NPC1RAB9A | |
| SCHEMBL32681842 | 0.79 | DPP7 (0.35) | NPC1RAB9A | |
| SCHEMBL25388192 | 0.78 | GPR119 (0.45) | GPR119HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4436966-A1 | BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | Arvinas Operations, Inc. (US) | 2024-10-02 | — | — | EP | disclosed |
| WO-2023097031-A1 | BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2023-06-01 | — | — | WO | disclosed |