Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PORCN | Q9H237 | 2/20 | 0.69 |
| ▸ | KIT | P10721 | 1/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13188268 | 0.83 | EGFR (0.51) | PORCNALDH1A1GAA | |
| SCHEMBL3717976 | 0.82 | MCL1 (0.52) | PORCNALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL29735406 | 0.81 | ALDH1A1 (0.51) | PORCNALDH1A1MAPTGAAKDM4E | |
| SCHEMBL3712306 | 0.81 | ALDH1A1 (0.51) | PORCNALDH1A1MAPTGAAKDM4E | |
| SCHEMBL15140688 | 0.80 | PORCN (0.64) | PORCNALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL30407873 | 0.80 | CYP17A1 (0.55) | PORCN | |
| SCHEMBL30408014 | 0.80 | PLAU (0.64) | PORCNALDH1A1MAPTGAAKDM4E | |
| SCHEMBL30407133 | 0.78 | ALDH1A1 (0.72) | PORCNALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL30800091 | 0.77 | ALDH1A1 (0.54) | ALDH1A1MAPTKDM4ELMNATP53 | |
| SCHEMBL30408571 | 0.76 | ALDH1A1 (0.51) | PORCNALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064458-A1 | SELECTIVE JAK2 INHIBITORS AND METHODS OF USE | YALE UNIVERSITY (US) | 2023-04-20 | — | — | WO | disclosed |