Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26089894 | 0.86 | MCL1 (0.40) | MCL1BAK1GRM5ALDH1A1L3MBTL1 | |
| SCHEMBL26090272 | 0.81 | CNR1 (0.39) | MCL1BAK1GRM5ALDH1A1CNR1 | |
| SCHEMBL21967017 | 0.77 | L3MBTL1 (0.46) | MCL1BAK1GRM5ALDH1A1L3MBTL1 | |
| SCHEMBL29744714 | 0.77 | L3MBTL1 (0.46) | MCL1BAK1GRM5ALDH1A1L3MBTL1 | |
| SCHEMBL30407862 | 0.77 | GRM5 (0.37) | MCL1BAK1GRM5CNR1 | |
| SCHEMBL26438017 | 0.77 | GRM5 (0.37) | MCL1BAK1GRM5CNR1 | |
| SCHEMBL26088997 | 0.75 | FEN1 (0.42) | MCL1BAK1GRM5L3MBTL1CNR1 | |
| SCHEMBL19586153 | 0.74 | L3MBTL1 (0.48) | MCL1BAK1GRM5ALDH1A1L3MBTL1 | |
| SCHEMBL26087060 | 0.74 | CNR1 (0.39) | MCL1BAK1ALDH1A1L3MBTL1CNR1 | |
| SCHEMBL24206919 | 0.73 | APP (0.45) | GRM5L3MBTL1PKMCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023069708-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND USES THEREOF | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-04-27 | — | — | WO | disclosed |