SCHEMBL30408683

SCHEMBL30408683

CC1Cc2c(sc(N)c2-c2nc3cc(F)ccc3s2)CN1C(=O)OC(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ILK Q13418 1/20 0.39
MYC P01106 2/20 0.37
F2RL3 Q96RI0 3/20 0.35
DYRK1A Q13627 3/20 0.35
MKNK1 Q9BUB5 3/20 0.34
AHR P35869 1/20 0.34
ADORA1 P30542 1/20 0.34
KDM4E B2RXH2 1/20 0.34
MAPT P10636 1/20 0.34
LMNA P02545 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
P2RY1 P47900 1/20 0.33
MAP4K4 O95819 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18293350 1.00 ILK (0.39) ILKMYCF2RL3DYRK1AMKNK1
SCHEMBL20248834 0.90 L3MBTL1 (0.40) ILKMYCDYRK1AMKNK1ADORA1
SCHEMBL30407882 0.90 ILK (0.42) ILKMYCDYRK1AADORA1KDM4E
SCHEMBL18293093 0.90 ILK (0.42) ILKMYCDYRK1AADORA1KDM4E
SCHEMBL18293284 0.90 MYC (0.37) ILKMYCDYRK1AMKNK1ADORA1
SCHEMBL18293209 0.90 MYC (0.37) ILKMYCDYRK1AMKNK1ADORA1
SCHEMBL30407403 0.90 MYC (0.37) ILKMYCDYRK1AMKNK1ADORA1
SCHEMBL30408451 0.90 MYC (0.37) ILKMYCDYRK1AMKNK1ADORA1
SCHEMBL18286053 0.88 ILK (0.42) ILKMYCF2RL3DYRK1AAHR
SCHEMBL18285929 0.88 APEX1 (0.43) MYCKDM4EMAPTLMNARXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230144106-A1 COMPOUNDS FOR THE MODULATION OF MYC ACTIVITY SYROS PHARMACEUTICALS INC (US) 2023-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230144106-A1 COMPOUNDS FOR THE MODULATION OF MYC ACTIVITY MYC, MYCBP, MYCBP2 ILK 1671/4885MYC 1/4885F2RL3 2304/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.