Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30410343 | 0.99 | SMN1; SMN2 (0.41) | NPC1RAB9ASMN1; SMN2HPGDIRAK4 | |
| SCHEMBL17460370 | 0.84 | HPGD (0.44) | NPC1RAB9ASMN1; SMN2HPGDIRAK4 | |
| SCHEMBL15020746 | 0.77 | PIK3CG (0.41) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL4312241 | 0.77 | IRAK4 (0.45) | NPC1RAB9ASMN1; SMN2HPGDIRAK4 | |
| SCHEMBL9741997 | 0.75 | ALDH1A1 (0.38) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL30574607 | 0.71 | PIK3CG (0.38) | IRAK4PIK3CGPDE2A | |
| SCHEMBL17460386 | 0.71 | IRAK4 (0.45) | NPC1RAB9ASMN1; SMN2HPGDIRAK4 | |
| SCHEMBL30267313 | 0.70 | PIK3CG (0.39) | HPGDIRAK4PIK3CGPDE2A | |
| SCHEMBL30393636 | 0.69 | PDE2A (0.39) | HPGDIRAK4ALDH1A1APOBEC3APIK3CG | |
| SCHEMBL14786046 | 0.69 | BID (0.46) | HPGDALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116348468-A | CFTR modulator compounds, compositions and uses thereof | 日东制药株式会社 | 2023-06-27 | — | — | CN | disclosed |