Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SPTLC1 | O15269 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15020746 | 0.85 | PIK3CG (0.41) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30410343 | 0.76 | SMN1; SMN2 (0.41) | ALDH1A1APOBEC3AHPGDNPC1RAB9A | |
| SCHEMBL30409028 | 0.75 | NPC1 (0.40) | ALDH1A1APOBEC3AHPGDNPC1RAB9A | |
| Ammonia Solution, Strong SCHEMBL7201308 | 0.74 | PIK3CG (0.40) | ALDH1A1APOBEC3AHPGD | |
| Formamide SCHEMBL7067260 | 0.71 | USP2 (0.36) | ALDH1A1APOBEC3AHPGD | |
| SCHEMBL9737283 | 0.70 | PTGDR2 (0.47) | ALDH1A1APOBEC3APTGDR2RAB9A | |
| SCHEMBL9737634 | 0.68 | KDM4E (0.48) | ALDH1A1APOBEC3APTGDR2HPGDSMN1; SMN2 | |
| SCHEMBL2359114 | 0.66 | HTR6 (0.41) | ALDH1A1APOBEC3AHPGDNPC1RAB9A | |
| SCHEMBL30393510 | 0.65 | PDE2A (0.39) | ALDH1A1APOBEC3AHPGDAPOBEC3G | |
| SCHEMBL1243349 | 0.64 | SMPD3 (0.51) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114944-A | Anxiolytic and anticonvulsant agents; muscle relaxants | A. H. ROBINS COMPANY INCORPORATED (US) | 1992-05-19 | — | — | US | disclosed |
| US-5114944-A | Anxiolytic and anticonvulsant agents; muscle relaxants | A. H. ROBINS COMPANY INCORPORATED (US) | 1992-05-19 | — | — | US | disclosed |