Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 11/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 10/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30409365 | 1.00 | GPR119 (0.43) | GPR119NR1H2NR1H3ABCB1USP30 | |
| SCHEMBL24215992 | 1.00 | GPR119 (0.43) | GPR119NR1H2NR1H3ABCB1USP30 | |
| SCHEMBL30409435 | 0.87 | GPR119 (0.41) | GPR119NR1H2NR1H3ABCB1USP30 | |
| SCHEMBL24216086 | 0.87 | GPR119 (0.41) | GPR119NR1H2NR1H3ABCB1USP30 | |
| SCHEMBL5782035 | 0.84 | GPR119 (0.46) | GPR119NR1H2NR1H3USP30MET | |
| SCHEMBL25350511 | 0.82 | UNG (0.41) | — | |
| SCHEMBL21336726 | 0.82 | GPR119 (0.56) | GPR119NR1H2NR1H3ABCB1 | |
| SCHEMBL24216237 | 0.80 | GPR119 (0.42) | GPR119NR1H2NR1H3USP30MET | |
| SCHEMBL30409934 | 0.80 | GPR119 (0.42) | GPR119NR1H2NR1H3USP30MET | |
| SCHEMBL5782039 | 0.79 | MAPT (0.47) | GPR119NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116133658-A | Novel compounds as inhibitors of histone deacetylase 6 and pharmaceutical compositions comprising the same | 株式会社 钟根堂 | 2023-05-16 | — | — | CN | disclosed |