Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 13/20 | 0.58 |
| ▸ | UCHL5 | Q9Y5K5 | 2/20 | 0.48 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.48 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25352274 | 1.00 | HDAC6 (0.58) | HDAC6UCHL5UCHL1UCHL3HDAC1 | |
| SCHEMBL25352360 | 0.88 | HDAC6 (0.51) | HDAC6HDAC1 | |
| SCHEMBL30460209 | 0.88 | HDAC6 (0.51) | HDAC6HDAC1 | |
| SCHEMBL25352849 | 0.88 | HDAC6 (0.51) | HDAC6HDAC1 | |
| SCHEMBL25351958 | 0.88 | HDAC6 (0.52) | HDAC6UCHL5HDAC1HDAC3HDAC2 | |
| SCHEMBL31535160 | 0.88 | HDAC6 (0.57) | HDAC6HDAC1 | |
| SCHEMBL25349454 | 0.88 | HDAC6 (0.57) | HDAC6HDAC1 | |
| SCHEMBL29398947 | 0.88 | HDAC6 (0.67) | HDAC6HDAC1 | |
| SCHEMBL24216054 | 0.88 | HDAC6 (0.67) | HDAC6HDAC1 | |
| SCHEMBL25351229 | 0.87 | HDAC6 (0.50) | HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157398-B | Oxadiazole-based selective histone deacetylase 6 inhibitors | 意大发马克股份公司 | 2025-03-11 | — | — | CN | claimed |
| EP-4185586-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2023-05-31 | — | — | EP | disclosed |
| CN-116133658-A | Novel compounds as inhibitors of histone deacetylase 6 and pharmaceutical compositions comprising the same | 株式会社 钟根堂 | 2023-05-16 | — | — | CN | disclosed |