Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.49 |
| ▸ | KDR | P35968 | 3/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.49 |
| ▸ | TEK | Q02763 | 2/20 | 0.49 |
| ▸ | UCHL5 | Q9Y5K5 | 2/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24215759 | 1.00 | HDAC6 (0.50) | HDAC6HDAC3HDAC1KDRHDAC2 | |
| SCHEMBL24215752 | 0.94 | KDM4E (0.53) | HDAC6HDAC3HDAC1KDRHDAC2 | |
| SCHEMBL30409092 | 0.94 | KDM4E (0.53) | HDAC6HDAC3HDAC1KDRHDAC2 | |
| SCHEMBL25352910 | 0.92 | HDAC6 (0.49) | HDAC6HDAC3HDAC1KDRHDAC2 | |
| SCHEMBL25207943 | 0.90 | UCHL5 (0.56) | HDAC6HDAC3HDAC1KDRHDAC2 | |
| SCHEMBL30425502 | 0.90 | UCHL5 (0.56) | HDAC6HDAC3HDAC1KDRHDAC2 | |
| SCHEMBL25350756 | 0.89 | HDAC6 (0.53) | HDAC6HDAC3HDAC1KDRHDAC2 | |
| SCHEMBL24216211 | 0.89 | HDAC6 (0.49) | HDAC6HDAC3HDAC1KDRHDAC2 | |
| SCHEMBL24216545 | 0.89 | KDM4E (0.44) | HDAC6HDAC3HDAC1KDRHDAC2 | |
| SCHEMBL30408530 | 0.89 | HDAC6 (0.49) | HDAC6HDAC3HDAC1KDRHDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4185586-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2023-05-31 | — | — | EP | disclosed |
| CN-116133658-A | Novel compounds as inhibitors of histone deacetylase 6 and pharmaceutical compositions comprising the same | 株式会社 钟根堂 | 2023-05-16 | — | — | CN | disclosed |