Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1839407 | 1.00 | THRA (0.50) | THRATHRBPPARDLTB4RLTB4R2 | |
| SCHEMBL530112 | 0.90 | THRA (0.58) | THRATHRBLTB4RLTB4R2MEN1 | |
| SCHEMBL29859888 | 0.90 | THRA (0.58) | THRATHRBLTB4RLTB4R2MEN1 | |
| SCHEMBL1838225 | 0.88 | THRA (0.65) | THRATHRBMEN1NR1I2LMNA | |
| SCHEMBL30409234 | 0.88 | THRA (0.65) | THRATHRBMEN1NR1I2LMNA | |
| SCHEMBL30185875 | 0.87 | L3MBTL1 (0.47) | THRATHRBMEN1MAPTKMT2A | |
| SCHEMBL1835772 | 0.87 | L3MBTL1 (0.47) | THRATHRBMEN1MAPTKMT2A | |
| SCHEMBL1835734 | 0.87 | THRA (0.68) | THRATHRBLTB4RLTB4R2MEN1 | |
| SCHEMBL1837003 | 0.87 | THRA (0.68) | THRATHRBLTB4RLTB4R2MEN1 | |
| SCHEMBL1840956 | 0.87 | THRA (0.68) | THRATHRBLTB4RLTB4R2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023080257-A1 | METHOD FOR PRODUCING ISOCYANATE COMPOUNDS, METHOD FOR PRODUCING CARBAMATE COMPOUNDS, METHOD FOR RECOVERING AMINE COMPOUNDS, AND ISOCYANATE COMPOSITION | 旭化成株式会社 | 2023-05-11 | — | — | WO | disclosed |