Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30409256 | 0.86 | NPSR1 (0.52) | NPSR1POLBTDP1ALDH1A1HTT | |
| SCHEMBL30408992 | 0.86 | NPSR1 (0.55) | NPSR1POLBTDP1ALDH1A1HTT | |
| SCHEMBL30409279 | 0.82 | NPSR1 (0.51) | NPSR1POLBALDH1A1HTTCTSD | |
| SCHEMBL30409307 | 0.81 | NPSR1 (0.50) | NPSR1POLBALDH1A1HTTCTSD | |
| SCHEMBL30410326 | 0.81 | NPSR1 (0.62) | NPSR1POLBTDP1ALDH1A1HTT | |
| SCHEMBL30407896 | 0.81 | NPSR1 (0.49) | NPSR1POLBALDH1A1HTTCTSD | |
| SCHEMBL8020617 | 0.73 | ALDH1A1 (0.55) | NPSR1POLBTDP1ALDH1A1HTT | |
| SCHEMBL8020606 | 0.73 | ALDH1A1 (0.55) | NPSR1POLBTDP1ALDH1A1HTT | |
| SCHEMBL30408092 | 0.72 | NPSR1 (0.78) | NPSR1POLBTDP1ALDH1A1HTT | |
| SCHEMBL30409911 | 0.71 | NPSR1 (0.52) | NPSR1ALDH1A1HTTCTSDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116102442-A | Method for preparing alpha-aryl amino acid ester by asymmetric catalysis | 西南大学 | 2023-05-12 | — | — | CN | disclosed |