SCHEMBL30409307

SCHEMBL30409307

CC(C)(C)OC(=O)CC[C@@](N)(C(=O)OC(C)(C)C)c1ccccc1[N+](=O)[O-]

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.50
ALDH1A1 P00352 3/20 0.40
HTT P42858 2/20 0.40
CTSD P07339 1/20 0.39
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
GAA P10253 1/20 0.37
GFER P55789 1/20 0.37
KDM4E B2RXH2 1/20 0.37
NR1D1 P20393 6/20 0.37
SMN1; SMN2 Q16637 2/20 0.35
RAB9A P51151 2/20 0.35
F2 P00734 1/20 0.35
NPC1 O15118 1/20 0.35
MAPT P10636 1/20 0.35
NR1H3 Q13133 1/20 0.35
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30408992 0.85 NPSR1 (0.55) NPSR1ALDH1A1HTTCTSDKMT2A
SCHEMBL30407896 0.84 NPSR1 (0.49) NPSR1ALDH1A1HTTCTSDKMT2A
SCHEMBL30409256 0.82 NPSR1 (0.52) NPSR1ALDH1A1HTTCTSDKMT2A
SCHEMBL30409643 0.81 NPSR1 (0.51) NPSR1ALDH1A1HTTCTSDKMT2A
SCHEMBL30409279 0.81 NPSR1 (0.51) NPSR1ALDH1A1HTTCTSDKMT2A
SCHEMBL30410326 0.80 NPSR1 (0.62) NPSR1ALDH1A1HTTCTSDKMT2A
SCHEMBL17079754 0.71 CYP1A2 (0.42) ALDH1A1KMT2AMEN1KDM4ESMN1; SMN2
SCHEMBL8805015 0.71 MEN1 (0.51) ALDH1A1HTTKMT2AMEN1GAA
SCHEMBL30408092 0.71 NPSR1 (0.78) NPSR1ALDH1A1HTTCTSDKMT2A
SCHEMBL11206263 0.71 ALDH1A1 (0.46) NPSR1ALDH1A1HTTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116102442-A Method for preparing alpha-aryl amino acid ester by asymmetric catalysis 西南大学 2023-05-12 CN disclosed