Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL5 | Q9Y5K5 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | TEK | Q02763 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24215838 | 1.00 | UCHL5 (0.49) | UCHL5NPC1RAB9ARXFP1TSHR | |
| SCHEMBL25350937 | 0.92 | HDAC6 (0.44) | UCHL5HDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL25992763 | 0.92 | HDAC1 (0.42) | UCHL5HDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL25993017 | 0.91 | KDM4E (0.52) | UCHL5NPC1RAB9AHDAC1HDAC6 | |
| SCHEMBL24216545 | 0.90 | KDM4E (0.44) | UCHL5HDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL25352241 | 0.90 | HDAC1 (0.42) | UCHL5NPC1RAB9AHDAC1HDAC6 | |
| SCHEMBL30424907 | 0.90 | UCHL5 (0.51) | UCHL5NPC1RAB9ARXFP1TSHR | |
| SCHEMBL25267677 | 0.90 | UCHL5 (0.51) | UCHL5NPC1RAB9ARXFP1TSHR | |
| SCHEMBL30408994 | 0.90 | HDAC1 (0.44) | UCHL5HDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL25349206 | 0.90 | HDAC1 (0.44) | UCHL5HDAC1HDAC6HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4185586-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2023-05-31 | — | — | EP | disclosed |
| CN-116133658-A | Novel compounds as inhibitors of histone deacetylase 6 and pharmaceutical compositions comprising the same | 株式会社 钟根堂 | 2023-05-16 | — | — | CN | disclosed |