Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.45 |
| ▸ | NOS3 | P29474 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19858386 | 1.00 | NOS1 (0.45) | NOS1NOS3NOS2LMNAKMT2A | |
| SCHEMBL31606685 | 1.00 | NOS1 (0.45) | NOS1NOS3NOS2LMNAKMT2A | |
| SCHEMBL9952902 | 1.00 | NOS1 (0.45) | NOS1NOS3NOS2LMNAKMT2A | |
| SCHEMBL28179952 | 1.00 | NOS1 (0.45) | NOS1NOS3NOS2LMNAKMT2A | |
| SCHEMBL304099 | 1.00 | NOS1 (0.45) | NOS1NOS3NOS2LMNAKMT2A | |
| SCHEMBL27183262 | 1.00 | NOS1 (0.45) | NOS1NOS3NOS2LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL19858050 | 0.98 | NOS1 (0.44) | NOS1NOS3NOS2LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL2409207 | 0.98 | NOS1 (0.44) | NOS1NOS3NOS2LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL1825341 | 0.98 | NOS1 (0.44) | NOS1NOS3NOS2LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL1825344 | 0.98 | NOS1 (0.44) | NOS1NOS3NOS2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4401757-A | CONVERTING ANIMAL INSULIN TO DES-B30-INSULIN, REACTING WITH THREONINE | SHIONOGI & CO., LTD. (JP) | 1983-08-30 | — | — | US | claimed |
| US-4400465-A | FROM ANIMAL INSULIN BY EXCHANGING THE B30 ALANINE WITH THREONINE | SHIONOGI & CO., LTD. (JP) | 1983-08-23 | — | — | US | claimed |
| EP-0017938-B1 | PROCESS FOR PREPARING A B30-THREONINE INSULIN | SHIONOGI & CO., LTD. (JP) | 1983-08-03 | — | — | EP | claimed |
| US-4320197-A | THREONINE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1982-03-16 | — | — | US | claimed |
| US-4320196-A | ENZYMATIC CATALYZED REACTION WITH THREONINE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1982-03-16 | — | — | US | claimed |
| EP-0017938-A1 | Process for preparing a B30-threonine insulin | SHIONOGI & CO., LTD. (JP) | 1980-10-29 | — | — | EP | claimed |
| WO-2024168123-A1 | SYNTHESIS OF CORE 2 O-SIALYL LEWIS-X POLYSACCHARIDES | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) | 2024-08-15 | — | — | WO | disclosed |
| CN-117304131-A | Alpha-carbonyl alkenyl ester compound, and preparation method and application thereof | 广州医科大学 | 2023-12-29 | — | — | CN | disclosed |
| CN-113292430-B | Alpha-carbonyl alkenyl ester compound and preparation method and application thereof | 江西师范大学 | 2022-11-29 | — | — | CN | disclosed |
| WO-2022242322-A1 | PHTHALIMIDE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国药科大学 | 2022-11-24 | — | — | WO | disclosed |
| CN-114671775-A | Synthesis of free tert-butyl amino acid ester by boron trifluoride diethyl etherate catalysis | 富乐马鸿凯（大连）医药有限公司 | 2022-06-28 | — | — | CN | disclosed |
| CN-112979532-B | Phthalimide compound, preparation method and application | 中国药科大学 | 2021-10-19 | — | — | CN | disclosed |
| CN-113292430-A | Alpha-carbonyl alkenyl ester compound and preparation method and application thereof | 江西师范大学 | 2021-08-24 | — | — | CN | disclosed |
| US-4511505-A | THREONINE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 1985-04-16 | — | — | US | disclosed |
| US-4401757-A | CONVERTING ANIMAL INSULIN TO DES-B30-INSULIN, REACTING WITH THREONINE | SHIONOGI & CO., LTD. (JP) | 1983-08-30 | — | — | US | disclosed |
| US-4400465-A | FROM ANIMAL INSULIN BY EXCHANGING THE B30 ALANINE WITH THREONINE | SHIONOGI & CO., LTD. (JP) | 1983-08-23 | — | — | US | disclosed |
| EP-0017938-B1 | PROCESS FOR PREPARING A B30-THREONINE INSULIN | SHIONOGI & CO., LTD. (JP) | 1983-08-03 | — | — | EP | disclosed |
| US-4320197-A | THREONINE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1982-03-16 | — | — | US | disclosed |
| US-4320196-A | ENZYMATIC CATALYZED REACTION WITH THREONINE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1982-03-16 | — | — | US | disclosed |
| EP-0017938-A1 | Process for preparing a B30-threonine insulin | SHIONOGI & CO., LTD. (JP) | 1980-10-29 | — | — | EP | disclosed |