Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.45 |
| ▸ | NOS3 | P29474 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19858386 | 1.00 | NOS1 (0.45) | NOS1NOS3NOS2LMNAKMT2A | |
| SCHEMBL31606685 | 1.00 | NOS1 (0.45) | NOS1NOS3NOS2LMNAKMT2A | |
| SCHEMBL28179952 | 1.00 | NOS1 (0.45) | NOS1NOS3NOS2LMNAKMT2A | |
| SCHEMBL304099 | 1.00 | NOS1 (0.45) | NOS1NOS3NOS2LMNAKMT2A | |
| SCHEMBL27183262 | 1.00 | NOS1 (0.45) | NOS1NOS3NOS2LMNAKMT2A | |
| SCHEMBL304098 | 1.00 | NOS1 (0.45) | NOS1NOS3NOS2LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL19858050 | 0.98 | NOS1 (0.44) | NOS1NOS3NOS2LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL2409207 | 0.98 | NOS1 (0.44) | NOS1NOS3NOS2LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL1825341 | 0.98 | NOS1 (0.44) | NOS1NOS3NOS2LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL1825344 | 0.98 | NOS1 (0.44) | NOS1NOS3NOS2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106414435-A | Amino-substituted isothiazoles | 拜耳制药股份公司 | 2017-02-15 | — | — | CN | claimed |
| US-12599684-B2 | Molecular probes and methods of use | CASE WESTERN RESERVE UNIVERSITY (US) | 2026-04-14 | — | — | US | disclosed |
| US-20260035357-A1 | THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION | GILEAD SCIENCE INC (US) | 2026-02-05 | — | — | US | disclosed |
| US-12404262-B2 | Therapeutic compounds for HIV virus infection | GILEAD SCIENCES, INC. (US) | 2025-09-02 | — | — | US | disclosed |
| CN-119060329-B | Enzyme response polyamino acid, self-adaptive bionic mechanical gradient hydrogel and preparation method and application thereof | 中国科学院长春应用化学研究所 | 2025-03-07 | — | — | CN | disclosed |
| US-20240399776-A1 | COLOR DEVELOPER, THERMAL RECORDING MATERIAL, AND THERMAL RECORDING LAYER COATING MATERIAL | SANKO CO., LTD. (JP) | 2024-12-05 | — | — | US | disclosed |
| CN-119060329-A | Enzyme response polyamino acid, self-adaptive bionic mechanical gradient hydrogel and preparation method and application thereof | 中国科学院长春应用化学研究所 | 2024-12-03 | — | — | CN | disclosed |
| EP-4440701-A1 | THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION | GILEAD SCIENCES, INC. (US) | 2024-10-09 | — | — | EP | disclosed |
| US-20240293553-A1 | P-SELECTIN INHIBITORS AND USES THEREOF | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) | 2024-09-05 | — | — | US | disclosed |
| WO-2024168123-A1 | SYNTHESIS OF CORE 2 O-SIALYL LEWIS-X POLYSACCHARIDES | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) | 2024-08-15 | — | — | WO | disclosed |
| WO-2012088282-A1 | MULTI-ARM POLYMERIC PRODRUG CONJUGATES OF PEMETREXED-BASED COMPOUNDS | NEKTAR THERAPEUTICS (US) | 2012-06-28 | — | — | WO | disclosed |
| US-20110263539-A1 | SHIP 1 MODULATOR COMPOUNDS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2011-10-27 | — | — | US | disclosed |
| CN-1875102-B | Novel plasmid and use thereof | DAIICHI FINE CHEM CO LTD | 2011-03-23 | — | — | CN | disclosed |
| US-20100323990-A1 | SHIP 1 MODULATOR PRODRUGS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2010-12-23 | — | — | US | disclosed |
| US-20100168225-A1 | Small-Molecule Hepatitis C Virus (HCV) NS3/4A Serine Protease Inhibitors | JEAN FRANCOIS | 2010-07-01 | — | — | US | disclosed |
| CN-1875102-A | Novel plasmid and use thereof | DAIICHI FINE CHEM CO LTD (JP) | 2006-12-06 | — | — | CN | disclosed |
| CN-1168673-A | New dipeptide p-amidinobenzylamides with N-terminal sulfonyl or aminosulfonyl radicals | BASF AG (DE) | 1997-12-24 | — | — | CN | disclosed |
| CN-1041757-A | The single stage method of tert-butyl threonine is synthetic | UNIV JILIN (CN) | 1990-05-02 | — | — | CN | disclosed |
| US-4766110-A | INHIBITS ANGIOTENSIN CONVERTING ENZYME, HYPOTENSIVE AGENTS | RYAN JAMES W (US) | 1988-08-23 | — | — | US | disclosed |
| US-4343898-A | Process for preparing esters of human insulin | NOVO INDUSTRI A/S (DK) | 1982-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168225-A1 | Small-Molecule Hepatitis C Virus (HCV) NS3/4A Serine Protease Inhibitors | SRR, HAVCR2, CBR3 | NOS1 523/4885NOS3 52/4885NOS2 431/4885 |
| US-20100323990-A1 | SHIP 1 MODULATOR PRODRUGS | PPM1D, PPM1G, PPM1F | NOS1 1710/4885NOS3 3315/4885NOS2 2577/4885 |
| US-20110263539-A1 | SHIP 1 MODULATOR COMPOUNDS | PPM1F, PPM1D, PPP1R1B | NOS1 1685/4885NOS3 3284/4885NOS2 2960/4885 |
| US-12404262-B2 | Therapeutic compounds for HIV virus infection | HAVCR2, MAVS, CD4 | NOS1 2449/4885NOS3 1219/4885NOS2 1844/4885 |
| US-20240293553-A1 | P-SELECTIN INHIBITORS AND USES THEREOF | SELP, SELPLG, SELE | NOS1 1497/4885NOS3 1400/4885NOS2 1474/4885 |
| US-20260035357-A1 | THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION | CCR10, CCR1, CCR3 | NOS1 1238/4885NOS3 539/4885NOS2 2648/4885 |
| US-12599684-B2 | Molecular probes and methods of use | TFRC, FGB, SSTR3 | NOS1 1161/4885NOS3 263/4885NOS2 874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.