Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 16/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | IKBKB | O14920 | 1/20 | 0.50 |
| ▸ | CHUK | O15111 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30410249 | 0.93 | CHRM5 (0.61) | CHRM5HSD11B1IKBKBCHUKCHRM1 | |
| SCHEMBL26347491 | 0.85 | CHRM5 (0.53) | CHRM5HSD11B1IKBKBCHUK | |
| SCHEMBL30410419 | 0.85 | CHRM5 (0.53) | CHRM5HSD11B1IKBKBCHUK | |
| SCHEMBL1148015 | 0.82 | IKBKB (0.68) | CHRM5IKBKBCHUK | |
| SCHEMBL16684845 | 0.80 | ULK1 (0.50) | — | |
| SCHEMBL27477822 | 0.76 | ULK1 (0.47) | — | |
| SCHEMBL22341666 | 0.74 | HSD11B1 (0.63) | CHRM5HSD11B1AURKA | |
| SCHEMBL142543 | 0.74 | ULK1 (0.56) | — | |
| SCHEMBL263519 | 0.74 | CHRM5 (0.58) | CHRM5 | |
| SCHEMBL10114822 | 0.74 | CHRM5 (0.56) | CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115768771-A | Arylsulfonyl derivatives and their use as muscarinic acetylcholine receptor M5 inhibitors | 范德堡大学 | 2023-03-07 | — | — | CN | claimed |