Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.39 |
| ▸ | FLT3 | P36888 | 2/20 | 0.38 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30411208 | 0.95 | TDP1 (0.44) | TDP1CTSLYTHDC1NPC1RAB9A | |
| SCHEMBL30410836 | 0.95 | YTHDC1 (0.48) | TDP1CTSLYTHDC1NPC1RAB9A | |
| SCHEMBL30410804 | 0.87 | CDK1 (0.48) | TDP1CTSLYTHDC1NPC1RAB9A | |
| SCHEMBL30411086 | 0.85 | TDP1 (0.60) | TDP1CTSLNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30410403 | 0.84 | YTHDC1 (0.46) | TDP1CTSLYTHDC1NPC1RAB9A | |
| SCHEMBL30410451 | 0.83 | CDK1 (0.52) | TDP1CTSLNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30410561 | 0.83 | ADORA3 (0.56) | TDP1ADORA3ADORA1ADORA2A | |
| SCHEMBL30410767 | 0.83 | YTHDC1 (0.49) | TDP1CTSLYTHDC1NPC1RAB9A | |
| SCHEMBL30410760 | 0.83 | TDP1 (0.42) | TDP1CTSLYTHDC1NPC1RAB9A | |
| SCHEMBL30411196 | 0.83 | ADORA3 (0.51) | TDP1CTSLADORA3ADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4178959-A1 | NITROGEN HETEROCYCLIC CYTOKININ DERIVATIVES, COMPOSITIONS CONTAINING THESE DERIVATIVES AND USE THEREOF | Univerzita Palackého v Olomouci (CZ) | 2023-05-17 | — | — | EP | disclosed |