Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.48 |
| ▸ | GLP1R | P43220 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15259316 | 0.93 | TSHR (0.49) | TSHREPHX2GLP1RALDH1A1ADRA1A | |
| SCHEMBL16241868 | 0.93 | TSHR (0.50) | TSHRGLP1RALDH1A1ADRA1AKDM4E | |
| SCHEMBL13165265 | 0.90 | TSHR (0.49) | TSHREPHX2GLP1RALDH1A1KDM4E | |
| SCHEMBL13640790 | 0.90 | TSHR (0.49) | TSHREPHX2GLP1RALDH1A1KDM4E | |
| SCHEMBL13641016 | 0.90 | TSHR (0.49) | TSHREPHX2GLP1RALDH1A1KDM4E | |
| SCHEMBL18923938 | 0.90 | TSHR (0.56) | TSHREPHX2GLP1RALDH1A1ADRA1A | |
| SCHEMBL18923980 | 0.90 | TSHR (0.56) | TSHREPHX2GLP1RALDH1A1ADRA1A | |
| SCHEMBL12666089 | 0.88 | TSHR (0.62) | TSHREPHX2ALDH1A1ADRA1AKDM4E | |
| SCHEMBL12666182 | 0.88 | TSHR (0.62) | TSHREPHX2ALDH1A1ADRA1AKDM4E | |
| SCHEMBL26297954 | 0.88 | ALDH1A1 (0.53) | TSHREPHX2ALDH1A1ADRA1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4426729-A1 | SPECIFIC CONJUGATION FOR AN ANTIBODY-DRUG CONJUGATE | Hangzhou Dac Biotech Co., Ltd. (CN) | 2024-09-11 | — | — | EP | disclosed |
| WO-2023078273-A1 | SPECIFIC CONJUGATION FOR AN ANTIBODY-DRUG CONJUGATE | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-05-11 | — | — | WO | disclosed |