Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 16/20 | 0.68 |
| ▸ | ATM | Q13315 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30409879 | 0.98 | HRH3 (0.67) | HRH3ATML3MBTL1KCNH2MEN1 | |
| SCHEMBL30410433 | 0.98 | HRH3 (0.67) | HRH3ATML3MBTL1KCNH2MEN1 | |
| SCHEMBL30409990 | 0.98 | HRH3 (0.65) | HRH3ATML3MBTL1KCNH2MEN1 | |
| SCHEMBL30409967 | 0.97 | MEN1 (0.66) | HRH3ATML3MBTL1KCNH2MEN1 | |
| SCHEMBL30410512 | 0.97 | MEN1 (0.66) | HRH3ATML3MBTL1KCNH2MEN1 | |
| SCHEMBL491848 | 0.95 | HRH3 (0.69) | HRH3KCNH2 | |
| Hydrochloric Acid SCHEMBL5692315 | 0.94 | HRH3 (0.68) | HRH3KCNH2 | |
| SCHEMBL5856367 | 0.94 | HRH3 (0.68) | HRH3KCNH2 | |
| SCHEMBL2005536 | 0.94 | HRH3 (0.67) | HRH3KCNH2 | |
| SCHEMBL27593 | 0.91 | PSMB1 (0.69) | HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4168396-A1 | COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | Universite De Franche Comte (FR) | 2023-04-26 | — | — | EP | disclosed |