Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.47 |
| ▸ | PNMT | P11086 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20765004 | 1.00 | MTNR1A (0.49) | MTNR1AMTNR1BPPARGSLC22A12PNMT | |
| SCHEMBL20764644 | 0.92 | PPARG (0.46) | MTNR1AMTNR1BPPARGSLC22A12PNMT | |
| SCHEMBL30412857 | 0.92 | PPARG (0.46) | MTNR1AMTNR1BPPARGSLC22A12PNMT | |
| SCHEMBL23679245 | 0.91 | MTNR1A (0.48) | MTNR1AMTNR1BPPARGSLC22A12PNMT | |
| SCHEMBL20764675 | 0.88 | PNMT (0.48) | PNMTALDH1A1POLBCES2MEN1 | |
| SCHEMBL380780 | 0.88 | PNMT (0.48) | PNMTALDH1A1POLBCES2MEN1 | |
| SCHEMBL20792310 | 0.87 | PNMT (0.47) | PNMTALDH1A1POLBCES2MEN1 | |
| SCHEMBL10216749 | 0.86 | PNMT (0.49) | PPARGSLC22A12PNMTALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL20764638 | 0.86 | PNMT (0.46) | PNMTALDH1A1POLBCES2MEN1 | |
| Hydrochloric Acid SCHEMBL381985 | 0.85 | PNMT (0.48) | PPARGSLC22A12PNMTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111372928-B | Benzimidazole derivatives as potassium channel inhibitors | 阿塞西翁制药公司 | 2023-05-16 | — | — | CN | disclosed |