Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ACP3 | P15309 | 3/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | TDO2 | P48775 | 1/20 | 0.48 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.47 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31295268 | 1.00 | PNMT (0.54) | PNMTKMT2ASMN1; SMN2ACP3CES2 | |
| SCHEMBL382119 | 1.00 | PNMT (0.54) | PNMTKMT2ASMN1; SMN2ACP3CES2 | |
| Hydrochloric Acid SCHEMBL21817757 | 0.98 | PNMT (0.53) | PNMTKMT2ASMN1; SMN2ACP3CES2 | |
| Hydrochloric Acid SCHEMBL21817760 | 0.98 | PNMT (0.53) | PNMTKMT2ASMN1; SMN2ACP3CES2 | |
| SCHEMBL20546159 | 0.91 | SLC1A3 (0.53) | PNMTKMT2ASMN1; SMN2ACP3EPHX1 | |
| SCHEMBL20546158 | 0.91 | SLC1A3 (0.53) | PNMTKMT2ASMN1; SMN2ACP3EPHX1 | |
| SCHEMBL20546815 | 0.89 | EPHX1 (0.51) | PNMTKMT2ASMN1; SMN2ACP3EPHX1 | |
| SCHEMBL20546819 | 0.89 | EPHX1 (0.51) | PNMTKMT2ASMN1; SMN2ACP3EPHX1 | |
| SCHEMBL7090175 | 0.88 | KMT2A (0.56) | PNMTKMT2ASMN1; SMN2EPHX1SLC6A9 | |
| SCHEMBL7090184 | 0.88 | KMT2A (0.56) | PNMTKMT2ASMN1; SMN2EPHX1SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111344281-B | Potassium channel inhibitors substituted benzimidazoles | 阿塞西翁制药公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-111372928-B | Benzimidazole derivatives as potassium channel inhibitors | 阿塞西翁制药公司 | 2023-05-16 | — | — | CN | disclosed |