Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | PPARG | P37231 | 4/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | EPOR | P19235 | 1/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6831085 | 1.00 | KMT2A (0.56) | KMT2ASMN1; SMN2PPARGPPARAKDM4E | |
| SCHEMBL7090175 | 1.00 | KMT2A (0.56) | KMT2ASMN1; SMN2PPARGPPARAKDM4E | |
| Hydrochloric Acid SCHEMBL7090826 | 0.99 | KMT2A (0.55) | KMT2ASMN1; SMN2PPARGPPARAKDM4E | |
| Hydrochloric Acid SCHEMBL7090645 | 0.99 | KMT2A (0.55) | KMT2ASMN1; SMN2PPARGPPARAKDM4E | |
| SCHEMBL31295268 | 0.88 | PNMT (0.54) | KMT2ASMN1; SMN2MEN1POLBSLC6A9 | |
| SCHEMBL30412972 | 0.88 | PNMT (0.54) | KMT2ASMN1; SMN2MEN1POLBSLC6A9 | |
| SCHEMBL382119 | 0.88 | PNMT (0.54) | KMT2ASMN1; SMN2MEN1POLBSLC6A9 | |
| Hydrochloric Acid SCHEMBL21817757 | 0.86 | PNMT (0.53) | KMT2ASMN1; SMN2MEN1POLBSLC6A9 | |
| Hydrochloric Acid SCHEMBL21817760 | 0.86 | PNMT (0.53) | KMT2ASMN1; SMN2MEN1POLBSLC6A9 | |
| SCHEMBL7087851 | 0.85 | KMT2A (0.70) | KMT2ASMN1; SMN2KDM4EEPORFNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7501429-B2 | Pyrimidine compounds as anti-ictogenic and/or anti-epileptogenic agents | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2009-03-10 | — | — | US | disclosed |
| US-20030194375-A1 | Administering 3-aminopropionic acid derivative as anticonvulsant | QUEEN'S UNIVERSITY AT KINGSTON AND NEUROCHEM, INC. | 2003-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030194375-A1 | Administering 3-aminopropionic acid derivative as anticonvulsant | SLC1A2, SLC1A1, SLC1A3 | KMT2A 1066/4885SMN1; SMN2 3205/4885PPARG 2404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.