Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCR | P30988 | 4/20 | 0.55 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.54 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 4/20 | 0.53 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | GLP1R | P43220 | 3/20 | 0.51 |
| ▸ | CCKBR | P32239 | 2/20 | 0.51 |
| ▸ | NPY2R | P49146 | 7/20 | 0.50 |
| ▸ | NPY4R | P50391 | 7/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.50 |
| ▸ | NPY1R | P25929 | 5/20 | 0.50 |
| ▸ | GCGR | P47871 | 1/20 | 0.49 |
| ▸ | GIPR | P48546 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29620320 | 0.93 | CALCR (0.60) | CALCRHCRTR1HCRTR2F2CRHR1 | |
| SCHEMBL38664551 | 0.87 | CALCR (0.51) | CALCRCRHR1CRHR2NPY2RNPY4R | |
| SCHEMBL29662249 | 0.87 | CALCR (0.58) | CALCRHCRTR1HCRTR2F2 | |
| SCHEMBL29530736 | 0.87 | C5AR1 (0.50) | CALCRHCRTR1HCRTR2F2CRHR1 | |
| SCHEMBL30906452 | 0.86 | CALCR (0.67) | CALCRHCRTR1HCRTR2F2CRHR1 | |
| SCHEMBL30275529 | 0.85 | F2 (0.53) | CALCRHCRTR1HCRTR2F2CRHR1 | |
| SCHEMBL29530620 | 0.84 | CRHR1 (0.49) | CALCRHCRTR1HCRTR2F2CRHR1 | |
| SCHEMBL29423354 | 0.84 | F2 (0.53) | CALCRHCRTR1HCRTR2F2CRHR1 | |
| SCHEMBL29530661 | 0.84 | REN (0.49) | CALCRHCRTR1HCRTR2F2 | |
| SCHEMBL29530837 | 0.84 | CRHR1 (0.50) | CALCRHCRTR1HCRTR2F2CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114437180-B | Protein tyrosine phosphatase 1B inhibiting peptide and application thereof | 青岛市市立医院 | 2023-05-19 | — | — | CN | claimed |
| CN-114437180-B | Protein tyrosine phosphatase 1B inhibiting peptide and application thereof | 青岛市市立医院 | 2023-05-19 | — | — | CN | disclosed |
| CN-114437180-B | Protein tyrosine phosphatase 1B inhibiting peptide and application thereof | 青岛市市立医院 | 2023-05-19 | — | — | CN | disclosed |