SCHEMBL30416331

SCHEMBL30416331

C[C@@H](N)C(=O)N[C@H](Cc1ccc(Cl)cc1)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MME P08473 10/20 0.55
ACE P12821 9/20 0.55
CPA1 P15085 8/20 0.55
ACE2 Q9BYF1 8/20 0.55
CA2 P00918 1/20 0.54
KMT2A Q03164 1/20 0.49
CTRB1 P17538 2/20 0.49
ALDH1A1 P00352 1/20 0.49
LMNA P02545 1/20 0.49
SLC6A2 P23975 1/20 0.49
SLC6A3 Q01959 1/20 0.49
FOLH1 Q04609 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30340429 1.00 MME (0.55) MMEACECPA1ACE2CA2
SCHEMBL30656931 0.90 ALDH1A1 (0.58) MMEACECPA1ACE2ALDH1A1
SCHEMBL31287928 0.87 ACE (0.65) MMEACECPA1ACE2FOLH1
SCHEMBL2493049 0.87 ACE (0.65) MMEACECPA1ACE2FOLH1
SCHEMBL2545591 0.87 ACE (0.65) MMEACECPA1ACE2FOLH1
SCHEMBL4073351 0.87 ACE (0.65) MMEACECPA1ACE2FOLH1
Alanyl-Dl-Phenylalanine SCHEMBL28743188 0.86 MME (0.65) MMEACECPA1ACE2CTRB1
Alanyl-Dl-Phenylalanine SCHEMBL893241 0.86 MME (0.65) MMEACECPA1ACE2CTRB1
Alanyl-Dl-Phenylalanine SCHEMBL893240 0.86 MME (0.65) MMEACECPA1ACE2CTRB1
Alanyl-Dl-Phenylalanine SCHEMBL4238049 0.86 MME (0.65) MMEACECPA1ACE2CTRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112159461-B Synthesis method of cetrorelix 开封明仁药业有限公司 2023-03-10 CN disclosed