Alanyl-Dl-Phenylalanine

Alanyl-Dl-Phenylalanine

SCHEMBL893241

CC(N)C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MME P08473 8/20 0.65
CTRB1 P17538 3/20 0.64
ACE P12821 5/20 0.63
CPA1 P15085 5/20 0.63
ACE2 Q9BYF1 5/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alanyl-Dl-Phenylalanine SCHEMBL27689824 1.00 MME (0.65) MMECTRB1ACECPA1ACE2
Alanyl-Dl-Phenylalanine SCHEMBL28142228 1.00 MME (0.65) MMECTRB1ACECPA1ACE2
Alanyl-Dl-Phenylalanine SCHEMBL28127119 1.00 MME (0.65) MMECTRB1ACECPA1ACE2
Alanyl-Dl-Phenylalanine SCHEMBL2597740 1.00 MME (0.65) MMECTRB1ACECPA1ACE2
Alanyl-Dl-Phenylalanine SCHEMBL4238049 1.00 MME (0.65) MMECTRB1ACECPA1ACE2
Alanyl-Dl-Phenylalanine SCHEMBL893240 1.00 MME (0.65) MMECTRB1ACECPA1ACE2
Alanyl-Dl-Phenylalanine SCHEMBL28743188 1.00 MME (0.65) MMECTRB1ACECPA1ACE2
Alanyl-Dl-Phenylalanine SCHEMBL28142226 1.00 MME (0.65) MMECTRB1ACECPA1ACE2
SCHEMBL29702065 0.97 MME (0.61) MMECTRB1ACECPA1ACE2
SCHEMBL10646215 0.94 MME (0.58) MMECTRB1ACECPA1ACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009143489-A2 MODULATION OF ANGIOGENESIS BY A-BETA PEPTIDE FRAGMENTS ARCHER PHARMACEUTICALS, INC. (US) 2009-11-26 WO claimed
US-5374551-A Measurement of metabolism of alpha-methyl glucoside BIOLOG, INC. (US) 1994-12-20 US claimed
US-12577274-B2 Manufacture of glucagon peptides BACHEM HOLDING AG (CH) 2026-03-17 US disclosed
US-20210122782-A1 MANUFACTURE OF GLUCAGON PEPTIDES BACHEM HOLDING AG (CH) 2021-04-29 US disclosed
US-10690635-B2 Purification of glucagon-like peptide 1 analogs BACHEM HOLDING AG (CH) 2020-06-23 US disclosed
US-20190113483-A1 PURIFICATION OF GLUCAGON-LIKE PEPTIDE 1 ANALOGS BACHEM HOLDING AG (CH) 2019-04-18 US disclosed
US-10161929-B2 Theranostics platform and methods of use Sanford Burnham Prebys Medical Discovery (US) 2018-12-25 US disclosed
CN-106565822-A Preparation method for chiral L-alanyl-phenylalanine 湖北泓肽生物科技有限公司 2017-04-19 CN disclosed
CN-106565822-A Preparation method for chiral L-alanyl-phenylalanine 湖北泓肽生物科技有限公司 2017-04-19 CN disclosed
CN-106565822-A Preparation method for chiral L-alanyl-phenylalanine 湖北泓肽生物科技有限公司 2017-04-19 CN disclosed
US-8981137-B2 Method for producing a concentrate of eicosapentaenoic and docosahexaenoic acids GOLDEN OMEGA S.A. (CL) 2015-03-17 US disclosed
US-20140005425-A1 METHOD FOR PRODUCING A CONCENTRATE OF EICOSAPENTAENOIC AND DOCOSAHEXAENOIC ACIDS GOLDEN OMEGA S.A. (CL) 2014-01-02 US disclosed
US-8586772-B2 Method for producing a concentrate of eicosapentaenoic and docosahexaenoic acid esters GOLDEN OMEGA S.A. (CL) 2013-11-19 US disclosed
WO-2013123403-A1 THERANOSTICS PLATFORM AND METHODS OF USE SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) 2013-08-22 WO disclosed
US-20120083616-A1 METHOD FOR PRODUCING A CONCENTRATE OF EICOSAPENTAENOIC AND DOCOSAHEXAENOIC ACID ESTERS GOLDEN OMEGA S.A. (CL) 2012-04-05 US disclosed
WO-2011026091-A1 IMIDAZOPYRIDAZINE COMPOUNDS FOR TREATING VIRAL INFECTIONS GLAXOSMITHKLINE LLC (US) 2011-03-03 WO disclosed
US-20090143279-A1 Methods and compositions for treating metabolic disorders PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2009-06-04 US disclosed
WO-1996007407-A1 METHODS OF PRODUCING CARDIOTONIC EFFECT AND IMPROVING CARDIAC CONTRACTILE FUNCTION BY ADMINISTRATION OF CARNOSINE WAKE FOREST UNIVERSITY (US) 1996-03-14 WO disclosed
EP-0081122-A1 Carrier tripeptides with antifungal activity Helopharm W. Petrik GmbH & Co.KG. (DE) 1983-06-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577274-B2 Manufacture of glucagon peptides IAPP, GLP1R, GCG MME 1328/4885CTRB1 443/4885ACE 1821/4885
US-20090143279-A1 Methods and compositions for treating metabolic disorders PC, PCK2, CS MME 1953/4885CTRB1 2442/4885ACE 1455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.